The Medicinal Mushroom Properties of Coriolus

 

Versicolor or PSK

Wildfire Natural Products

Featuring author Phil Steinberg

 

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(PSK) VPS - Coriolus versicolor - Standardized Extract


Wildfire Natural Products

Featuring author Phil Steinberg

 

(PSK) VPS -Coriolus versicolor - standardized extract Clinically Proven Adjunctive Treatment For Cancer

Following is general information and pricing on this exciting product, an all-natural non-toxic extract from the mushroom, Coriolus versicolor, standardized to contain a minimum concentration of 35% polysaccharides, including beta 1,3, beta 1,4 and beta 1,6 glucans.

Only available in Japan until now, where it has been trademarked as PSK, Coriolus versicolor extract is one of the most thoroughly researched all-natural products with proven benefit in cancer therapy. For the past 20 years, PSK has been widely used as an immuno-therapeutic agent, both by itself, and in conjunction with other conventional therapies. Significant immune system benefit has been clearly demonstrated in dozens of published clinical studies.

Colon Cancer- PSK Alone
Randomized Controlled Clinical Trial - 110 Patients After Curative Surgery for Colorectal Cancer - 10-Year Study

This study found that when compared with the control group, the leukocyte activity of the PSK group showed "remarkable enhancement." It was concluded that "the beneficial effects (of PSK) were probably due to the activation of leukocyte functions as one of the many biological-response-modifying activities induced by PSK."

In this study the increase in survival rate and disease free period after oral administration of PSK was found to be "statistically significant" when both rates were doubled over those of the control group.

Lung Cancer - PSK as Adjuvant Therapy after Radiotherapy
185 Patients with Non-Small Cell Lung Cancer Stages I-III - 10-Year Study

The use of PSK as immunotherapy in combination with radiotherapy was examined based on the recognized ability of PSK to "inhibit disorders of cellular immunity attributed to anti-cancer drugs,” and in doing so to “counteract the adverse effects of these drugs.”

The “five year survival rate of the patients (who received PSK) with stages I or II disease, as well as stage III was 39% and 22% respectively, compared with the non-administered (no PSK) group's 16% and 5%. These differences are statistically significant.”

Breast Cancer - PSK as Adjuvant Therapy with Chemotherapy
Randomized Controlled Clinical Trial - 227 Patients with Operable Breast Cancer Immuno-chemotherapy vs Chemotherapy - 10-Year Study

The use of PSK together with chemotherapy was explored with results indicating that PSK protects "against the suppression of immuno-activity which is caused by the administration of anti-cancer drugs," by "stimulation of the immuno-activity of the host."

In this study the survival rate of the group that took PSK with chemotherapy was 81.1% after 10 years. The survival rate of the group that used chemotherapy alone was 64.5%. The study concluded that Immuno-chemotherapy with PSK “improved the prognosis of patients with operable breast cancer with vascular invasion."

Gastric Cancer - PSK as Adjuvant Therapy with Chemotherapy
Randomized Controlled Clinical Trial - 262 Patients after Curative Gastrectomy Immuno-chemotherapy vs Chemotherapy - 5 Year Study

The benefit to the immune system of combining PSK with chemotherapy was attributed to "a restorative effect in patients who have been immuno-suppressed by both recent surgery and subsequent chemotherapy."

In this study, published in Lancet, the survival rate of the group that took PSK with chemotherapy was 73% after 5 years. The survival rate of the group that used chemotherapy alone was 60%. The study concluded that combining PSK with chemotherapy was "beneficial for preventing recurrence of cancer and in prolonging survival for patients who have undergone curative gastrectomy."

Acute Leukemia - PSK as Adjuvant Therapy with Chemotherapy
Control Group Study - 28 Patients - Immuno-chemotherapy vs Chemotherapy

This study found that "the durations of complete remission and survival in the chemo-immunotherapy group showed significant prolongation compared to that of the chemotherapy group." This study also indicates that PSK enhances depressed immune systems without abnormal stimulation to immune cancers.

Dosage
The majority of studies, including the ones cited in this letter, used a dosage of 3 grams of PSK per day for two full years after the subjects cancer was in remission. In some of the studies, a declining dosage was continued after 2 years of disease free health. Each capsule of our Coriolus extract contains 625 mg, requiring 5 capsules daily to equal the 3 gram dosage. It is recommended that the daily dose be split between morning and evening, taking 3 capsules in the morning and 2 capsules in the evening, as close to 12 hours apart as possible, preferably on an empty stomach or with a light meal. In cases where the cancer has metastasized beyond its primary location, the amounts may be increased up to as much as 10 capsules per day. For general preventative purposes, one might use 1 capsule twice daily

Absorption
The extract is absorbed, in its original form, through the intestinal tract and into the bloodstream. It is distributed throughout the body but shows higher concentrations in the bone marrow, salivary, lymph and hormonal glands, the brain, spleen, and liver, and tumors. It has an 18 hour half-life and is eliminated in 72 hours, primarily through respiration.

Including Coriolus extract as an adjunctive nutritional supplement in your diet, can provide enormous potential benefit for maintaining or improving immune system health, with virtually no risk. You will appreciate the years of study and research that are behind Coriolus versicolor and the proven results that have come with regular use. You, will also appreciate that as a non-toxic food product, this extract can be safely used in almost any nutritional or therapeutic health management plan.

References:
1. Torisu, M., et al. (1990). Significant prolongation of disease-free period gained by oral polysaccharide K (PSK) administration after curative surgical operation of colorectal cancer. Cancer Immunology Immunotherapy 31(5),261-268.
2. Hayakawa, K., et al. (1993). Effect of Krestin (PSK) as Adjuvant Treatment on the Prognosis after Radical Radiotherapy in Patients with Non-Small Cell Lung Cancer. Anticancer Research 13,1815-1820.
3. Llino, Y., et al. (1995). Immuno-chemotherapies vs Chemotherapy as Adjuvant Treatment after Curative Resection of Operable Breast Cancer. Anticancer Research 15, 2907-2912.
4. Nakazato, H., et al. (1994). Efficacy of Immuno-chemotherapy as Adjuvant Treatment after Curative Resection of Gastric Cancer. Lancet 343,1122-1126.
5. Nagao, T., et al. (1981). Chemo-immunotherapy with Krestin (PSK) in Acute Leukemia. Tokai J EXP Clin Med.6(2), 141-146.
6. Torisu, M., et al. (1990). Significant prolongation of disease-free period gained by oral polysaccharide K (PSK) administration after curative surgical operation of colorectal cancer. Cancer Immunology Immunotherapy 31(5), 261-268.
7. Ikuzawa, M., et al. (1988). Fate and Distribution of an Antitumor Protein-Bound Polysaccharide PSK (Krestin). International Journal of Immunopharmacology 10(4),415-423.

IMPORTANT NOTICE: The information provided above has not been evaluated by the FDA, is for educational purposes only and is not intended to replace proper medical care, diagnose or prescribe. The use of Coriolus versicolor extract is meant to be used as nutritional support, not for the treatment of any disease. Your medical condition should be discussed with your physician before using this product.

(Doctor/Pharmacist inquiries invited)

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  Kate Clifton

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