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Orthomolecular Medicine Explained |
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Wunderlich Orthomolecular Medicine Revisited Ray C. Wunderlich, Jr., M.D.' Orthomolecular treatment of clinical conditions
amounts to only a small percentage of total percentage of total medical care
rendered in North America. Persons with health disorders who seek treatment from
their physicians are likely to receive a wide variety of
drugs. In recent years, however, a
concerned citizenry, uneasy, perhaps, about the ready use of powerful drugs, has
increasingly sought alternatives to drug therapy for medical
disorders. Despite this strong trend,
however, the toximolecular approach (the use of xenobiotics, substances foreign
to the body) remains strong whenever patients consult physicians for
illness. Hyperactive and attention-deficit children usually receive Ritalin or similar drugs. Peptic
ulcer patients nearly always receive Zantac or Tagamet, Neurotic, psychotic, and
character-disordered patients usually receive tranquilizers (neuroleptics) of
one sort or another. The calcium-channel blocking drugs appear to be clinically effective agents and are helpful in promoting understanding about basic cellular orthomolecular disease management are available, "These methods are employed by orthomolecular physician CD. The components of these treatments include dietary manipulation, nutrition supplementation, herbal remedies, homeopathic treatments, detoxification, hype bane oxygen, intravenous chelation, allergy management, attitude adjustment ecological manipulation, and safe forms of megavitamin therapy. Newer methods of treatment such as ozone therapy, intravenous hydrogen
peroxide therapy, magn o therapy, and the like may be utilized but must be
considered experimental at this time. Although double-blind studies are an important part of the scientific endeavor to find the truth, so, too, are observations. The scientific achievements of the 20th century have been based upon the successful descriptive work of the 19th century. Then, too, in a broad sense science incorporates philosophy. Some point out that science, too, must recognize that experiments once observed by a observer, become changed by the act of observation. The character of scientific procedures places restriction on the relevance of results. Philosophers of science are obliged to consider not merely nature in isolation but also the manner in which man, himself perceives and interprets facts. Recognizing that the problems posed by the interaction of
man and nature are complex, we may conclude that all information can be valuable
when placed in proper perspective. The man sought orthomolecular treatment because
of medication side effects that he had experienced through the years. Body
chemical analysis identified low levels of most minerals, especially magnesium,
He was placed on mineral supplements with particular attention to magnesium. He
was also treated with an herbal mixture period, without change in diet or
exercise, the man was free of prescription medications and his blood pressure
remained entirely in the normal range. He sought another treatment option. The man was placed on a program
consisting of L-tryptophan at bedtime (1000 mgs.) and L-phenylalanine (1000 mg.)
in the a.m. At noon he took phosphatidyl choline (1200 mg.) along with
supporting vitamins and minerals. Among these were 6 grams of vitamin C and 150
mgs. of niacin daily. The man remained on this regimen for a year with good
results. With good sleep at night and markedly improved bowel pattern, his days
were no longer restless and he was able to focus on his work. Furthermore, his
thoughts became distinctly "upbeat" and his self-confidence greatly
improved. The values were: Fasting 62 mg present 1/2 hour 80 mg present 1 hour 76 mg present 2 hours 74 mg present 3 hours 64 mg present 4 hours 34 mg present 5 hours 48 mg present 6 hours 58 mg present The glucose tolerance curve was abnormal (low, flat curve with abnormally low 4 hour nadir). The diagnosis of low blood sugar was established. Suzy was placed on a microalgae supplement and treated with glucose tolerance factor derived from yeast. She was instructed in proper diet and commenced eating fish, shellfish, vegetables, whole grains, and some fresh fruits. In between meals she snacked on soy cheese, tofu and brown rice wafers, seeds, or nuts. She promptly ceased gaining weight and soon was losing
weight at the rate of 1-2 pounds per week. She became more alert, lost her
afternoon somnolence and had no further headaches. Whenever she ate sweets or
missed meals she noted a return of "brain fog". After 6 months, however, she was
able to consume an occasional sweet without adverse
effects. Laboratory testing of hair showed high levels of lead and cadmium. Blood mineral analysis indicated low levels of calcium, magnesium, and zinc and corroborated an excess of lead. No evident source of heavy metals was able to be found in the environment. Supplements of calcium, magnesium, and zinc were administered. Vitamin C, administered by means of a buffered, neutral pH powder, was increased in dosage gradually to bowel tolerance. The lad was able to consume 5 grams daily. Other supporting vitamins were also taken. A prompt improvement in the youth's behavior occurred. Fewer bad days were noted and on those days the boy was able to be dealt with by his parents whereas previously there was no control. As time passed, the mood swings abated. Six months after
the institution of treatment, follow up tests showed improved levels of calcium,
magnesium and zinc. Lead excess was found again but the levels of lead were only
half of the original levels. Cadmium was not found to be excessive at this time.
Continued supplementation was carried out. The source of heavy metal excess was
never found but the boy's behaviour was steady at a good level as long as he
took his supplements. Nutritional laboratory testing documented abnormally low levels of vitamin A A and deficits of many minerals including iron. When appropriate nutrient supplements were taken she lost her irritable
nature. She herself agreed that life was better. Her menses became much more
comfortable. She became amenable to dietary counsel. ling whereas previously she
had eaten as she wished according to no particular guidelines, often skipping
meals. Laboratory testing revealed multiple abnormalities of body chemistry, Deficit minerals included calcium, magnesium, manganese, chromium, and cobalt. Levels of vitamin B12 and folic acid were depressed and vitamin B1 was also low Treatment was commenced with intravenous vitamin C, 12 1/2 grams, with added calcium, magnesium, B complex, and B,, .Intravenous treatments were rendered daily for 5 days then 3 times the next week, and gradually less thereafter. Oral supplements of B complex, B, and minerals were taken. The response to treatment was prompt and reduced her consumption of coffee and eventually was able to function very well with no dietary source of caffeine. She became a responsive family member. Her sexual interest and responsivity grew as she became less and less depressed. From time to time,
whenever the "pressures of life'' became too great for her, a booster was
necessary. For the most part, however, the previously depressed woman was happy
and fulfilled. He was placed on an orthomolecular program consisting of niacinamide, vitamin C, pantothenic acid, and vitamin B, A substantial multiple vitamin was given, too. Within 3 months, the parents reported good gains. The boy was now attending school and had begun to participate in some social affairs. Addition of glutamic
acid appeared to accelerate the progress. He has now graduated from high school
and holds down a job. His treatment regimen currently consists of a high potency
multiple vitamin each day. A metabolic investigation was carried out. Abnormal protein metabolism was identified. Levels of the amino acid, cystine, were very low in the blood and urine. Ta urine was also low. Two toxic peptides, carnosine and anserine, were considerably elevated. Treatment was commenced with a diet restricting the dietary sources of carnosine and anserine, predominantly red meat. Careful survey of iron stores was carried out. Since the enzyme subserving carnosine and and serine is zinc-dependent, he was placed on supplemental zinc. Cystine and taurine were given. No further seizures occurred. He is now 6-years old. Through the years, the lad became hyperactive or attention deficit when he consumed meat. His intellect is normal, Follow up laboratory testing shows minimal elevation of carnosine and and serine with no other abnormalities. Reading Disorder A fourth-grade boy was evaluated due to severe reading problems characterized as poor comprehension. He was 11/2 grade levels behind in reading comprehension. Psychological testing showed depressed verbal score and normal performance score. Despite an enormous appetite for food, the lad's weight was low for his age and his rate of gain was slow. The stools were described as large and bulky with chronic offensive odor. The dietary history showed a "normal" intake of protein foods, that is, he ate eggs, hamburgers, milk, cheese, and other foods of the culture. Biochemical testing revealed very low levels of amino acids in the blood and urine. A urine indican test was strongly positive indicative of incomplete digestive proteolysis with absorption of toxic chemicals. Stool samples were sent for detailed exam (Comprehensive Digestive Stool Analysis). Undigested protein fibers were found in the stool along with excessive amounts of undigested fat. The boy was considered to have a chronic digestive and absorptive disorder. He was placed on nutritional supplements including amino acids and digestive enzymes. Within a few months his school performance advanced. Within a year's time, he was performing at grade level in reading. Moreover, the boy had gained several pounds of weight. He displayed an enhanced level of self-confidence and a heightened self-image that contrasted sharply with his former passive, retiring self. Discussion For better or worse, today, the "me" generation has become
increasingly aggressive about the pursuit of that which it is convinced is
important, Thus we witness progress in civil rights, personal rights, and
environmental causes. Hopefully, the
physician of the future will first use orthomolecular concepts to influence his
patients to make long term investments in health. Such a physician may need to
utilize pharmaceutical drugs for some persons some of the
time. In contrast, initial use of pharmaceutical drugs may create dependence upon such drugs for the maintenance of normal behaviour (the tranquilizer syndrome, for example, may create a permanent state of drug dependency and Tender recovery unlikely). When physicians come to know the full range of therapeutic options,
careful assessment of the risk/benefit ratio will indicate the desirability of
Orthomolecular Medicine.
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